Merilisa HIV Gen 4 is an enzyme immunoassay for the qualitative determination of HIV p24 antigen and antibodies to Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) in human serum or plasma. Merilisa HIV Gen 4 detects HIV p24 antigen in addition to IgG, IgA and IgM antibodies to the core and envelope glycoproteins of HIV 1-2 by using p24 monoclonal antibodies and recombinant proteins of gp41, gp120 and gp36 representing the immunodominant regions of HIV 1-2.

  • Streptavidin biotin technology
  • Simultaneous detection of Antibodies and Antigens
  • Monoclonal Antibodies for p24 Ag detection




  • Simultaneous detection of HIV p24 antigen and antibodies to Human Immunodeficiency virus types 1 (HIV- 1) and 2 (HIV - 2)


Product Specifications

Intended Use 4th Generation based immunoassay for qualitative determination of antibodies against HIV 1 and HIV 2 and p24 antigen
Principle Antigen and antibody Sandwich Immunoassay
Technique ELISA
Detection Antibodies to HIV -1 and HIV -2 (IgM, IgG and IgA) and p24 antigen
Capture gp 41 and gp 120 for HIV -1 and monoclonal Anti - p24 ; gp 36 for HIV -2
  Monoclonal anti-HIV p24 antibody conjugated to biotin
Conjugate Mixture of streptavidin and HIV antigen conjugated to HRP
Type of Specimen required Serum or Plasma
Total incubation time 90 minutes
Diagnostic Sensitivity 100%
Diagnostic Specificity > 99.5%
Evaluation National Institute of Biologicals


Ordering Information

Product Code Material Description Pack Size
HV4ELI-02 Merilisa HIV Gen 4 96 Wells

Clinical Data